Bilateral synchronous parathyroid carcinoma: a case report

Abstract

Parathyroid carcinoma (PC) is a rare endocrine neoplasm that most commonly occurs in patients with primary hyperparathyroidism, with an incidence of 0.5-4% among patients treated surgically for primary hyperparathyroidism. The diagnosis of PC is challenging as it clinically, radiologically, and histologically overlaps with parathyroid adenoma/hyperplasia. Diagnosis is based on clear evidence of local tissue invasion and/or metastasis. Bilateral PC is rare, and the primary treatment is surgical resection.